| Contact: | 1111 Budapest, Szt. Gellért tér 4. fszt. 15-16. |
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| Website: | link |
| Focal points and main thrusts of research: | |
| Introduction: | NMR service for the collegues of the faculty and for companies (on the basis of a contract). Structure elucidation/investigation of the measured probes (in a limited quantity). National (University of Szeged) and international (Hacettepe University, Ankara, Turkey) cooperation on the field of the structure investigation of natural and biological active compounds (eg.: ecdysteroids, triterpenes, flavanoids). Laboratory practice for students. |
| Sample publications: | G. Varró, P. Pálchuber, B. Pogrányi, A. Simon, L. Hegedűs, I. Kádas: (±)-trans-dihydronarciclasine and (±)-trans-dihydrolycoricidine analogues modified in their ring A: Evaluation of their anticancer activity and a SAR study Eur. J. Med. Chem. 173, 76-89 (2019) (https://doi.org/10.1016/j.ejmech.2019.04.010) M. Bojtár, A. Simon, P. Bombicz, I. Bitter: Expanding the Pillararene Chemistry: Synthesis and Application of a 10 + 1 Functionalized Pillar[5]arene Org. Lett. 19, 4528-4531 (2017) DOI: 10.1021/acs.orglett.7b02092 A. Hunyadi, I. Herke, K. Veres, A. Erdei, A. Simon, G. Tóth: Volatile Glycosides from the Leaves of Morus alba with a Potential Contribution to the Complex Anti-diabetic Activity Natural Product Communications 9 (2), 145-147 (2014) G. Szántó, L. Hegedűs, L. Mattyasovszky, A. Simon, Á. Simon, I. Bitter, G. Tóth, L. Tőke, I. Kádas: An expedient total synthesis of ent-(–)-7-deoxy-trans-dihydronarciclasine Tetrahedron 65, 8412-8417 (2009) A. Ványolós, A. Simon, G. Tóth, L. Polgár, Z. Kele, A. Ilku, P. Mátyus, M. Báthori: C-29 Ecdysteroids from Ajuga reptans var. reptans J. Nat. Prod. 72, 929-932 (2009) V. Csokai, A. Grün, B. Balázs, A. Simon, G. Tóth, I. Bitter: Functionalized thiacalix- and calyx[4]arene based Ag+ ionophores: synthesis and comparative NMR study Tetrahedron 62, 10215-10222 (2006) S. Moeller, D. Albert, H. Duddeck, A. Simon, G. Tóth, O. M. Demchuk, K. M. Pietrusiewicz: Chiral atropisomeric diiodobiphenyls – enantiodifferentiation by the dirhodium method Tetrahedron: Asymmetry 15, 3609-3616 (2004) H. Duddeck, G. Tóth, A. Simon: 17O NMR Parameters Landolt-Börnstein New Series III/35E, 2002, ISBN 3-540-42501-2, Springer Verlag, Berlin Heidelberg New York H. S. M. Soliman, A. Simon, G. Tóth, H. Duddeck: Identification and Structure Determination of Four Triterpene Saponins from some Middle-East Plants Magn. Reson. Chem. 39, 567-576 (2001) |
| Awards and achievements: | |
| Guest professors: | |
| Group leader: | Dr. Simon András |